hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14031.1

Complex Portal: CPX-21601

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
ANKRD28	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)	5	UniProt NCBI
ANKRD44	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)	4	UniProt NCBI
ANKRD52	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) (Ankyrin repeat domain-containing protein 52)	3	UniProt NCBI
CTCFL	Transcriptional repressor CTCFL (Brother of the regulator of imprinted sites) (CCCTC-binding factor) (CTCF paralog) (CTCF-like protein) (Cancer/testis antigen 27) (CT27) (Zinc finger protein CTCF-T)	5	UniProt NCBI
MRNIP	MRN complex-interacting protein (MRN-interacting protein)	5	UniProt NCBI
PPP6C	Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) [Cleaved into: Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed]	5	UniProt NCBI
PPP6R1	Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1)	5	UniProt NCBI
PPP6R2	Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)	5	UniProt NCBI
PPP6R3	Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)	5	UniProt NCBI
SPART	Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1)	5	UniProt NCBI

Showing 1 to 10 of 10 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:5196	3.98250603803e-09	0.4	PPP6C PPP6R1 PPP6R2 ANKRD28	TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1)
REAC:R-HSA-204005	1.36716025886e-05	0.4	PPP6C PPP6R1 ANKRD28 PPP6R3	COPII-mediated vesicle transport
REAC:R-HSA-171319	9.79763261181e-05	0.3	PPP6C ANKRD28 PPP6R3	Telomere Extension By Telomerase
REAC:R-HSA-199977	0.000425872013598	0.4	PPP6C PPP6R1 ANKRD28 PPP6R3	ER to Golgi Anterograde Transport
REAC:R-HSA-948021	0.000889205200481	0.4	PPP6C PPP6R1 ANKRD28 PPP6R3	Transport to the Golgi and subsequent modification
REAC:R-HSA-180786	0.00114054706802	0.3	PPP6C ANKRD28 PPP6R3	Extension of Telomeres
REAC:R-HSA-446203	0.00636866609671	0.4	PPP6C PPP6R1 ANKRD28 PPP6R3	Asparagine N-linked glycosylation
REAC:R-HSA-157579	0.00870109711608	0.3	PPP6C ANKRD28 PPP6R3	Telomere Maintenance
REAC:R-HSA-73886	0.0177651546753	0.3	PPP6C ANKRD28 PPP6R3	Chromosome Maintenance

Showing 1 to 9 of 9 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ANKRD28	PPP6C	1.0	0.156		hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM
ANKRD52	PPP6C	1.0	0.054		hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM
PPP6C	PPP6R1	1.0	0.26	structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM
PPP6C	ANKRD44	1.0	0.094	mutually_exclusive (Q9UPN7)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116
ANKRD28	ANKRD44	1.0	0.256		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
PPP6R2	PPP6C	1.0	0.082	structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM
PPP6R3	PPP6C	1.0	0.444	structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction boldt_WMM
PPP6R2	ANKRD44	1.0	0.126		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
ANKRD44	PPP6R1	1.0	0.018	structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116
PPP6R2	ANKRD28	1.0	0.092		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM boldt_WMM

Showing 1 to 10 of 43 entries

Related Complexes

Genename	Complexes
PPP6R2	huMAP3_01958.1 huMAP3_12079.1 huMAP3_14031.1
SPART	huMAP3_04387.1 huMAP3_12079.1 huMAP3_14031.1
ANKRD28	huMAP3_01958.1 huMAP3_12079.1 huMAP3_14031.1
PPP6R3	huMAP3_01958.1 huMAP3_12079.1 huMAP3_14025.1 huMAP3_14031.1
ANKRD52	huMAP3_01436.1 huMAP3_01958.1 huMAP3_06301.1 huMAP3_09431.1 huMAP3_12079.1 huMAP3_14031.1 huMAP3_14078.1
PPP6C	huMAP3_01958.1 huMAP3_12079.1 huMAP3_14031.1 huMAP3_14584.1
ANKRD44	huMAP3_01958.1 huMAP3_04387.1 huMAP3_12079.1 huMAP3_14031.1 huMAP3_14615.1
PPP6R1	huMAP3_01958.1 huMAP3_12079.1 huMAP3_13294.1 huMAP3_14031.1
MRNIP	huMAP3_01958.1 huMAP3_04387.1 huMAP3_12079.1 huMAP3_14031.1 huMAP3_14615.1
CTCFL	huMAP3_14031.1 huMAP3_14152.1 huMAP3_14959.1 huMAP3_15036.1