hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09980.1

Complex Portal: CPX-16926

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
ASB3	Ankyrin repeat and SOCS box protein 3 (ASB-3)	5	UniProt NCBI
RAB40AL	Ras-related protein Rab-40A-like (Ras-like GTPase)	4	UniProt NCBI
PCMTD2	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2	5	UniProt NCBI
NUDT6	Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG)	5	UniProt NCBI
WSB1	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1)	5	UniProt NCBI
RAB40C	Ras-related protein Rab-40C (Rar-like protein) (Ras-like protein family member 8C) (SOCS box-containing protein RAR3)	5	UniProt NCBI
ASB9	Ankyrin repeat and SOCS box protein 9 (ASB-9)	5	UniProt NCBI
AMBRA1	Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)	5	UniProt NCBI
SOCS5	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2 protein 6) (CIS-6) (Cytokine-inducible SH2-containing protein 5)	5	UniProt NCBI
NEDD8	NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)	5	UniProt NCBI
ASB1	Ankyrin repeat and SOCS box protein 1 (ASB-1)	5	UniProt NCBI
LRRC41	Leucine-rich repeat-containing protein 41 (Protein Muf1)	5	UniProt NCBI
TULP4	Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4)	5	UniProt NCBI
WSB2	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein)	3	UniProt NCBI
ELOB	Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)	5	UniProt NCBI
ELOC	Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)	5	UniProt NCBI
SOCS4	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7)	5	UniProt NCBI
RNF7	RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)	5	UniProt NCBI
SOCS7	Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4)	5	UniProt NCBI
SOCS6	Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)	5	UniProt NCBI
LRRC28	Leucine-rich repeat-containing protein 28	2	UniProt NCBI
ASB13	Ankyrin repeat and SOCS box protein 13 (ASB-13)	5	UniProt NCBI
CISH	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Protein G18) (Suppressor of cytokine signaling) (SOCS)	5	UniProt NCBI
SOCS3	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3)	5	UniProt NCBI
ISCA1	Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA) (hIscA)	5	UniProt NCBI
PCMTD1	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1	5	UniProt NCBI
RAB40A	Ras-related protein Rab-40A (SOCS box-containing protein RAR2A) (Protein Rar-2)	4	UniProt NCBI
SOCS2	Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)	5	UniProt NCBI
SPSB2	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9)	5	UniProt NCBI
RAB40B	Ras-related protein Rab-40B (SOCS box-containing protein RAR) (Protein Rar)	4	UniProt NCBI
ARIH2	E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein)	5	UniProt NCBI
CUL5	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8951664	1.4857005992e-24	0.59375	LRRC41 SOCS6 TULP4 ASB1 SOCS2 WSB2 CUL5 SOCS3 CISH NEDD8 ASB13 SOCS5 ASB3 ASB9 ELOC ELOB WSB1 SPSB2 RNF7	Neddylation
REAC:R-HSA-597592	1.67975769309e-14	0.6875	LRRC41 RAB40A SPSB2 SOCS6 ASB3 ELOB TULP4 WSB2 NEDD8 CISH ELOC SOCS5 SOCS2 ASB9 CUL5 RNF7 ASB13 WSB1 ASB1 RAB40B RAB40C SOCS3	Post-translational protein modification
REAC:R-HSA-983168	2.95920447152e-12	0.40625	LRRC41 RNF7 ASB1 SPSB2 CUL5 ARIH2 SOCS3 ASB3 ASB9 ELOC ELOB WSB1 ASB13	Antigen processing: Ubiquitination & Proteasome degradation
CORUM:208	5.07918267912e-12	0.15625	ASB1 CUL5 RNF7 ELOC ELOB	Ubiquitin E3 ligase (ASB1, TCEB1, TCEB2, CUL5, RNF7)
REAC:R-HSA-392499	1.65959184068e-11	0.6875	LRRC41 RAB40A SPSB2 SOCS6 ASB3 ELOB TULP4 WSB2 NEDD8 CISH ELOC SOCS5 SOCS2 ASB9 CUL5 RNF7 ASB13 WSB1 ASB1 RAB40B RAB40C SOCS3	Metabolism of proteins
GO:0046935	2.02544019854e-11	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	1-phosphatidylinositol-3-kinase regulator activity
REAC:R-HSA-983169	4.11685438609e-11	0.40625	LRRC41 RNF7 ASB1 SPSB2 CUL5 ARIH2 SOCS3 ASB3 ASB9 ELOC ELOB WSB1 ASB13	Class I MHC mediated antigen processing & presentation
GO:0031466	2.80198489354e-10	0.1875	RNF7 ARIH2 PCMTD1 ELOB CUL5 ELOC	Cul5-RING ubiquitin ligase complex
CORUM:211	2.65042636159e-09	0.125	ELOB CUL5 RNF7 ELOC	Ubiquitin E3 ligase (ASB12, TCEB1, TCEB2, CUL5, RNF7)
CORUM:6268	2.65042636159e-09	0.125	ELOB CUL5 ASB9 ELOC	Cullin-RING E3 ubiquitin ligase complex
GO:0005942	2.79051246459e-09	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	phosphatidylinositol 3-kinase complex
KEGG:04917	3.35079014112e-09	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	Prolactin signaling pathway
CORUM:207	1.32318150773e-08	0.125	ELOB CUL5 RNF7 ELOC	Ubiquitin E3 ligase (ASB2, TCEB1, TCEB2, CUL5, RNF7)
CORUM:210	1.32318150773e-08	0.125	ELOB CUL5 RNF7 ELOC	Ubiquitin E3 ligase (ASB7, TCEB1, TCEB2, CUL5, RNF7)
CORUM:214	1.32318150773e-08	0.125	ELOB CUL5 WSB1 ELOC	Ubiquitin E3 ligase (WSB1, TCEB1, TCEB2, CUL5, RBX1)
CORUM:209	1.32318150773e-08	0.125	ELOB CUL5 RNF7 ELOC	Ubiquitin E3 ligase (ASB6, TCEB1, TCEB2, CUL5, RNF7)
GO:1990234	4.7278995366e-08	0.5	SOCS7 RNF7 PCMTD1 ASB1 SOCS2 SPSB2 CUL5 SOCS3 SOCS5 SOCS6 AMBRA1 SOCS4 ELOC ELOB CISH ARIH2	transferase complex
REAC:R-HSA-1280218	1.48154337138e-07	0.40625	LRRC41 RNF7 ASB1 SPSB2 CUL5 ARIH2 SOCS3 ASB3 ASB9 ELOC ELOB WSB1 ASB13	Adaptive Immune System
GO:0046854	3.53238851276e-07	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	phosphatidylinositol phosphate biosynthetic process
REAC:R-HSA-9705462	3.59666956113e-07	0.15625	ELOB CUL5 SOCS3 RNF7 ELOC	Inactivation of CSF3 (G-CSF) signaling
KEGG:04630	6.85450443521e-07	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	JAK-STAT signaling pathway
REAC:R-HSA-9674555	1.04242742033e-06	0.15625	ELOB CUL5 SOCS3 RNF7 ELOC	Signaling by CSF3 (G-CSF)
REAC:R-HSA-168256	3.3064468873e-06	0.53125	LRRC41 RNF7 ASB1 SOCS2 SPSB2 CUL5 SOCS3 CISH SOCS5 SOCS6 ASB3 ASB9 ELOC ELOB WSB1 ARIH2 ASB13	Immune System
WP:WP3300	4.36508319369e-05	0.09375	ELOB CUL5 ELOC	Dual hijack model of Vif in HIV infection
GO:0032446	8.68736533199e-05	0.375	RNF7 ASB1 WSB2 CUL5 SPSB2 NEDD8 ARIH2 AMBRA1 ASB9 PCMTD1 ELOC WSB1	protein modification by small protein conjugation
GO:0031461	0.000112424505292	0.25	RNF7 SPSB2 ARIH2 ELOB AMBRA1 PCMTD1 ELOC CUL5	cullin-RING ubiquitin ligase complex
GO:0006661	0.000133834274968	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	phosphatidylinositol biosynthetic process
GO:0070647	0.000265007536394	0.375	RNF7 ASB1 WSB2 CUL5 SPSB2 NEDD8 ARIH2 AMBRA1 ASB9 PCMTD1 ELOC WSB1	protein modification by small protein conjugation or removal
GO:0000151	0.00027390354254	0.28125	RNF7 ASB1 SPSB2 ARIH2 PCMTD1 AMBRA1 ELOC ELOB CUL5	ubiquitin ligase complex
GO:0016567	0.000321013385343	0.34375	RNF7 ASB1 WSB2 SPSB2 ARIH2 CUL5 AMBRA1 ASB9 PCMTD1 ELOC WSB1	protein ubiquitination
GO:0046488	0.00039833176504	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	phosphatidylinositol metabolic process
GO:0043687	0.000553183654069	0.375	RNF7 ASB1 WSB2 CUL5 SPSB2 NEDD8 ARIH2 AMBRA1 ASB9 PCMTD1 ELOC WSB1	post-translational protein modification
KEGG:04120	0.000638247490065	0.15625	ELOB CUL5 SOCS3 RNF7 ELOC	Ubiquitin mediated proteolysis
CORUM:6738	0.000650497358995	0.0625	ELOB ELOC	PRAME-ElonginBC ubiquitin ligase
WP:WP5072	0.000676339110485	0.125	ELOB CUL5 RNF7 ARIH2	Modulators of TCR signaling and T cell activation
GO:0019898	0.000921526538834	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	extrinsic component of membrane
GO:1902494	0.00111080498369	0.5	SOCS7 RNF7 PCMTD1 ASB1 SOCS2 SPSB2 CUL5 SOCS3 SOCS5 SOCS6 AMBRA1 SOCS4 ELOC ELOB CISH ARIH2	catalytic complex
REAC:R-HSA-1280215	0.00128290093152	0.28125	RNF7 SOCS2 CUL5 SOCS6 SOCS5 CISH ELOC ELOB SOCS3	Cytokine Signaling in Immune system
WP:WP2034	0.0018382123193	0.125	SOCS2 SOCS7 SOCS3 CISH	Leptin signaling pathway
CORUM:7576	0.00194882117837	0.0625	ELOB ELOC	VHL-ElonginB-ElonginC complex
CORUM:5270	0.00194882117837	0.0625	ELOB ELOC	VHL-TCEB1-TCEB2 complex
GO:0046474	0.00296716844691	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	glycerophospholipid biosynthetic process
REAC:R-HSA-982772	0.00374130428733	0.09375	CISH SOCS3 SOCS2	Growth hormone receptor signaling
CORUM:6485	0.00389230851077	0.0625	ELOB ELOC	HIF1alpha-VHL-ElonginB-ElonginC complex
CORUM:622	0.00389230851077	0.0625	ELOB ELOC	Ubiquitin E3 ligase (VHL, TCEB1, TCEB2, CUL2)
CORUM:5267	0.00389230851077	0.0625	ELOB ELOC	VHL-VDU1-TCEB1-TCEB2 complex
WP:WP5358	0.00441031770491	0.09375	CISH SOCS3 SOCS2	JAK STAT signaling in the regulation of Beta cells
KEGG:04930	0.00595874861547	0.09375	SOCS2 SOCS4 SOCS3	Type II diabetes mellitus
CORUM:205	0.00647830433983	0.0625	ELOB ELOC	Ubiquitin E3 ligase (VHL, TCEB1, TCEB2, CUL2, RBX1)
GO:0008654	0.00718317189856	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	phospholipid biosynthetic process
GO:0045017	0.00919311672423	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	glycerolipid biosynthetic process
CORUM:7556	0.00970416155986	0.0625	ELOB ELOC	PRAME complex
GO:0019207	0.0112755528155	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	kinase regulator activity
WP:WP2864	0.0156325975309	0.09375	CUL5 RNF7 SOCS3	Apoptosis related network due to altered Notch3 in ovarian cancer
WP:WP4860	0.0169715086633	0.0625	ELOB ELOC	Hijack of ubiquitination by SARS CoV 2
GO:0030163	0.017643127793	0.34375	SOCS6 RNF7 ARIH2 SPSB2 NEDD8 SOCS5 AMBRA1 ASB9 ELOC ELOB CUL5	protein catabolic process
GO:0051603	0.0190933610782	0.3125	SOCS6 RNF7 ARIH2 SPSB2 SOCS5 NEDD8 AMBRA1 ELOC ELOB CUL5	proteolysis involved in protein catabolic process
GO:0006650	0.0303666051386	0.21875	CISH SOCS2 SOCS6 SOCS5 SOCS7 SOCS4 SOCS3	glycerophospholipid metabolic process
GO:0006511	0.0356595158556	0.28125	RNF7 ARIH2 SPSB2 SOCS5 NEDD8 AMBRA1 ELOC ELOB CUL5	ubiquitin-dependent protein catabolic process
REAC:R-HSA-8939242	0.0390858987398	0.0625	SOCS4 SOCS3	RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
GO:0019941	0.0408151682457	0.28125	RNF7 ARIH2 SPSB2 SOCS5 NEDD8 AMBRA1 ELOC ELOB CUL5	modification-dependent protein catabolic process
GO:0043632	0.0489549118416	0.28125	RNF7 ARIH2 SPSB2 SOCS5 NEDD8 AMBRA1 ELOC ELOB CUL5	modification-dependent macromolecule catabolic process
KEGG:05170	0.0492329111944	0.125	ELOB CUL5 RNF7 ELOC	Human immunodeficiency virus 1 infection

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RAB40C	RAB40B	1.0		mutually_exclusive (Q15369)
RAB40AL	RAB40A	1.0
ASB3	CUL5	1.0	0.044
ELOC	RAB40B	1.0		structurally_consistent (dimer)
CISH	CUL5	1.0
RNF7	CUL5	1.0	0.544	structurally_consistent (dimer)
ELOB	ELOC	1.0	0.944	mixed_interface
SOCS6	CUL5	1.0	0.228
SPSB2	CUL5	0.999		structurally_consistent (O95376)
SOCS2	CUL5	0.999		structurally_consistent (dimer)
RAB40C	CUL5	0.999	0.076
ARIH2	CUL5	0.999	0.036	structurally_consistent (dimer)
ELOC	RAB40C	0.999	0.12	structurally_consistent (dimer)
ISCA1	RAB40A	0.999
RAB40B	CUL5	0.999
RAB40AL	CUL5	0.999
TULP4	CUL5	0.999
WSB2	CUL5	0.999
LRRC41	CUL5	0.999	0.018
ELOB	SOCS6	0.999	0.147378787879
ELOB	RAB40C	0.999	0.142	mutually_exclusive (Q15369)
SOCS7	CUL5	0.998
SOCS5	CUL5	0.998		mutually_exclusive (Q15369)
ASB1	CUL5	0.998	0.096
ELOB	SPSB2	0.998		mixed_interface
ELOB	RAB40B	0.998		mutually_exclusive (Q15369)
LRRC28	CUL5	0.998
ELOB	CISH	0.998
RAB40A	ARIH2	0.998
RAB40C	RNF7	0.997	0.088
WSB1	CUL5	0.997
SOCS4	CUL5	0.997		structurally_consistent (dimer)
SPSB2	RNF7	0.997		structurally_consistent (O95376)
RNF7	SOCS2	0.997		mutually_exclusive (Q93034)
NEDD8	CUL5	0.997	0.066
SOCS5	RNF7	0.997
ASB1	RNF7	0.997	0.138
ASB13	RNF7	0.997
WSB1	RNF7	0.997
RNF7	SOCS6	0.997	0.102
SOCS4	RNF7	0.997		structurally_consistent (Q93034)
ASB9	ELOC	0.997	0.19	structurally_consistent (dimer)
RNF7	RAB40B	0.997
ASB3	RNF7	0.996	0.112
ELOC	SOCS6	0.996	0.172	structurally_consistent (O14508)
ELOC	CISH	0.996
ELOC	RAB40AL	0.996
ASB9	ELOB	0.995	0.134
ELOC	CUL5	0.995	0.226	structurally_consistent (dimer)
SOCS7	RNF7	0.995
SPSB2	NEDD8	0.995
ELOC	RNF7	0.995	0.162
ASB9	CUL5	0.995	0.072	structurally_consistent (O95376)
ELOB	RNF7	0.995	0.332
SOCS6	ARIH2	0.995	0.172
WSB2	RNF7	0.995
ISCA1	RAB40C	0.994	0.046
ELOC	ARIH2	0.994	0.336
ELOB	ARIH2	0.994	0.314
ASB13	CUL5	0.993
ASB3	ELOC	0.993	0.19	structurally_consistent (dimer)
ELOC	SPSB2	0.992		mixed_interface
ELOC	AMBRA1	0.992	0.21
LRRC41	RNF7	0.992	0.03
ELOB	RAB40A	0.991		mutually_exclusive (Q15369)
RNF7	CISH	0.991
PCMTD1	CUL5	0.991	0.034
RAB40A	CUL5	0.991
RNF7	PCMTD1	0.99	0.082
ASB3	ELOB	0.987	0.2	mutually_exclusive (Q15369)
AMBRA1	SOCS3	0.986
ISCA1	NUDT6	0.983	0.072
AMBRA1	WSB2	0.982
ELOB	RAB40AL	0.982
ELOC	RAB40A	0.981		structurally_consistent (dimer)
PCMTD2	RNF7	0.98	0.128
ASB9	RNF7	0.98	0.066	structurally_consistent (O95376)
ISCA1	CUL5	0.98	0.022
ISCA1	RAB40B	0.98
RAB40B	ARIH2	0.979
NEDD8	SOCS6	0.979	0.196
NEDD8	RAB40A	0.978
RNF7	ARIH2	0.978	0.166	structurally_consistent (dimer)
PCMTD2	CUL5	0.976	0.06
ELOB	SOCS3	0.976		mutually_exclusive (Q15369)
TULP4	RNF7	0.974
ELOC	SOCS3	0.974		structurally_consistent (dimer)
AMBRA1	CUL5	0.972	0.078
NEDD8	RNF7	0.971	0.31
RAB40C	ARIH2	0.969	0.104
ELOB	CUL5	0.968	0.248
ELOC	SOCS7	0.968
ELOC	WSB2	0.967
NEDD8	CISH	0.963
ELOC	NEDD8	0.962	0.458
ASB9	NEDD8	0.957	0.124
SPSB2	ARIH2	0.956		structurally_consistent (dimer)
ELOB	AMBRA1	0.952	0.208
ELOB	SOCS7	0.945
ELOB	WSB2	0.944
PCMTD2	PCMTD1	0.941	0.136
ISCA1	RAB40AL	0.94
SOCS5	SOCS2	0.925		mutually_exclusive (Q15369)
ASB13	SOCS5	0.925
SOCS5	SOCS6	0.925
WSB1	SOCS6	0.925
ASB13	WSB1	0.925
WSB1	SOCS2	0.925		mutually_exclusive (Q15369)
SOCS4	SOCS2	0.925		mutually_exclusive (Q15369)
SOCS4	SOCS6	0.925
ASB13	SOCS4	0.925
ASB13	SOCS7	0.918
ASB1	ASB3	0.917	0.046	mutually_exclusive (Q15369)
ASB3	RAB40C	0.917	0.066	mutually_exclusive (Q15369)
ISCA1	ELOC	0.915	0.14
SOCS5	SOCS4	0.913		mutually_exclusive (Q15369)
WSB1	SOCS4	0.913		mutually_exclusive (Q15369)
SOCS7	WSB1	0.913
SOCS7	SOCS5	0.913
SOCS7	SOCS4	0.913
WSB1	SOCS5	0.913		mutually_exclusive (Q15369)
ASB13	SOCS2	0.912
ASB13	SOCS6	0.912
SOCS5	CISH	0.907
WSB1	CISH	0.907
SOCS4	CISH	0.907
RAB40AL	ARIH2	0.905
RAB40AL	RAB40B	0.88
ELOB	TULP4	0.878
SOCS5	LRRC28	0.877
WSB1	LRRC28	0.877
SOCS4	LRRC28	0.877
ASB13	CISH	0.873
ASB13	LRRC28	0.868
LRRC28	SOCS2	0.868
SOCS7	LRRC28	0.868
SOCS6	LRRC28	0.868
ASB9	ARIH2	0.866	0.116	structurally_consistent (dimer)
ELOC	LRRC28	0.863
RAB40AL	RAB40C	0.863
SPSB2	SOCS5	0.861		mutually_exclusive (Q15369)
SPSB2	WSB1	0.861		mutually_exclusive (Q15369)
SOCS7	SOCS2	0.861
SOCS7	SOCS6	0.861
SPSB2	SOCS4	0.861		mutually_exclusive (Q15369)
ASB13	AMBRA1	0.86
NEDD8	SOCS2	0.857
ELOC	TULP4	0.854
ELOB	NEDD8	0.852	0.48
WSB2	SOCS5	0.852
SOCS5	RAB40B	0.852		mutually_exclusive (Q15369)
WSB1	RAB40B	0.852		mutually_exclusive (Q15369)
RAB40C	SOCS5	0.852		mutually_exclusive (Q15369)
RAB40C	SOCS4	0.852		mutually_exclusive (Q15369)
WSB2	SOCS4	0.852
SOCS6	SOCS2	0.852		structurally_consistent (dimer)
SOCS4	RAB40B	0.852		mutually_exclusive (Q15369)
WSB2	WSB1	0.852
WSB1	RAB40C	0.852		mutually_exclusive (Q15369)
AMBRA1	RAB40C	0.849	0.08
NEDD8	LRRC28	0.848
ISCA1	ELOB	0.846	0.08
ASB13	ASB1	0.844
ASB1	SOCS5	0.841		mutually_exclusive (Q15369)
ASB1	SOCS4	0.841		mutually_exclusive (Q15369)
ASB1	WSB1	0.841		mutually_exclusive (Q15369)
ASB13	RAB40C	0.834
ASB13	WSB2	0.834
ASB13	RAB40B	0.834
ASB13	SPSB2	0.834
SOCS7	CISH	0.83
ASB1	SOCS2	0.823		mutually_exclusive (Q15369)
SOCS7	SPSB2	0.823
ASB1	SOCS6	0.823	0.09
SOCS5	TULP4	0.821
TULP4	SOCS4	0.821
WSB1	TULP4	0.821
ASB1	PCMTD2	0.816	0.076
ASB3	SOCS4	0.812		mutually_exclusive (Q15369)
LRRC41	SOCS5	0.812
RAB40C	SOCS6	0.812	0.044
LRRC41	WSB1	0.812
WSB2	SOCS6	0.812
SOCS6	RAB40B	0.812
ASB3	SOCS5	0.812		mutually_exclusive (Q15369)
SOCS7	RAB40C	0.812
SPSB2	SOCS6	0.812
LRRC41	SOCS4	0.812
SOCS7	WSB2	0.812
SPSB2	SOCS2	0.812		mutually_exclusive (Q15369)
SOCS7	RAB40B	0.812
RAB40C	SOCS2	0.812		mutually_exclusive (Q15369)
ASB3	WSB1	0.812		mutually_exclusive (Q15369)
SOCS2	RAB40B	0.812		mutually_exclusive (Q15369)
WSB2	SOCS2	0.812
PCMTD1	SOCS2	0.802
ASB13	TULP4	0.8
ASB1	SOCS7	0.799
SOCS7	PCMTD1	0.795
SOCS3	CUL5	0.794
LRRC41	LRRC28	0.788
SOCS6	CISH	0.787
CISH	SOCS2	0.787
ASB1	CISH	0.786
TULP4	SOCS2	0.786
TULP4	SOCS6	0.786
PCMTD2	SOCS5	0.785
PCMTD2	SOCS4	0.785
PCMTD2	WSB1	0.785
ASB3	PCMTD2	0.784	0.142
ASB3	SOCS7	0.783
ASB13	PCMTD2	0.783
SOCS5	PCMTD1	0.778
WSB1	PCMTD1	0.778
SOCS4	PCMTD1	0.778
ASB3	SOCS6	0.778	0.136
ASB1	RAB40C	0.778	0.062	mutually_exclusive (Q15369)
ASB3	WSB2	0.778
ASB3	SOCS2	0.778		mutually_exclusive (Q15369)
ASB3	RAB40B	0.778		mutually_exclusive (Q15369)
ASB3	SPSB2	0.778		mutually_exclusive (Q15369)
LRRC41	TULP4	0.777
SOCS7	TULP4	0.775
ASB1	SPSB2	0.773		mutually_exclusive (Q15369)
ASB13	ASB3	0.765
LRRC41	ASB13	0.765
LRRC41	SOCS7	0.765
ASB1	WSB2	0.765
SPSB2	WSB2	0.765
ASB13	PCMTD1	0.763
LRRC41	WSB2	0.763
LRRC41	SOCS2	0.759
LRRC41	SOCS6	0.759	0.120888888889
SPSB2	RAB40B	0.759		mutually_exclusive (Q15369)
ASB1	RAB40B	0.759		mutually_exclusive (Q15369)
SPSB2	RAB40C	0.759		mutually_exclusive (Q15369)
LRRC41	ASB1	0.757	0.11
RAB40C	TULP4	0.754
ASB1	TULP4	0.754
ASB3	TULP4	0.754
SOCS6	PCMTD1	0.751	0.056
WSB2	RAB40C	0.75
WSB2	RAB40B	0.75
ASB1	PCMTD1	0.745	0.074
RAB40C	LRRC28	0.741
SPSB2	LRRC28	0.741
ASB1	LRRC28	0.741
RNF7	LRRC28	0.741
LRRC28	RAB40B	0.741
NEDD8	RAB40B	0.739
WSB2	TULP4	0.735
TULP4	RAB40B	0.735
SPSB2	TULP4	0.735
WSB2	LRRC28	0.735
LRRC41	SPSB2	0.734
ASB3	LRRC28	0.73
LRRC41	PCMTD2	0.728	0.07
NEDD8	ARIH2	0.72	0.108
ASB3	PCMTD1	0.719	0.108
AMBRA1	SOCS2	0.718
LRRC41	RAB40B	0.717
TULP4	LRRC28	0.716
SOCS7	PCMTD2	0.714
AMBRA1	ARIH2	0.708	0.142
AMBRA1	CISH	0.706
RAB40C	PCMTD1	0.697	0.038
AMBRA1	SPSB2	0.689
ISCA1	ARIH2	0.688	0.082
PCMTD2	TULP4	0.685
SPSB2	CISH	0.683
LRRC41	ASB3	0.681	0.096
PCMTD2	LRRC28	0.68
RAB40C	CISH	0.676
WSB2	CISH	0.676
CISH	RAB40B	0.676
ELOC	SOCS2	0.674		structurally_consistent (Q93034) structurally_consistent (dimer)
SPSB2	PCMTD1	0.671
WSB2	PCMTD1	0.671
TULP4	ARIH2	0.665
LRRC28	PCMTD1	0.644
ASB1	ARIH2	0.64	0.08
AMBRA1	RNF7	0.637	0.09
ASB3	CISH	0.633
ELOB	SOCS2	0.632
LRRC41	PCMTD1	0.631	0.014
LRRC41	CISH	0.625
AMBRA1	SOCS6	0.612	0.12
AMBRA1	RAB40B	0.608
PCMTD1	RAB40B	0.606
SOCS4	ARIH2	0.603
SOCS5	ARIH2	0.603
WSB1	ARIH2	0.603
SOCS7	ARIH2	0.603
ASB13	NEDD8	0.593
NEDD8	SOCS4	0.554
SOCS5	NEDD8	0.554
SOCS7	NEDD8	0.554
WSB1	NEDD8	0.554
RAB40C	NEDD8	0.553	0.1
LRRC28	ARIH2	0.55
WSB2	NEDD8	0.536
ASB1	NEDD8	0.515	0.138
TULP4	PCMTD1	0.512
WSB2	ARIH2	0.508
AMBRA1	RAB40A	0.49
ASB13	ARIH2	0.489
ELOB	LRRC28	0.485
CISH	PCMTD1	0.459
SPSB2	PCMTD2	0.451
SOCS2	ARIH2	0.448
ISCA1	AMBRA1	0.442	0.118
NEDD8	TULP4	0.438
ASB3	NEDD8	0.436	0.182
PCMTD2	RAB40B	0.428
LRRC41	RAB40C	0.425	0.054
PCMTD2	SOCS2	0.356
PCMTD2	RAB40C	0.351	0.086
PCMTD2	SOCS6	0.334	0.044
LRRC28	CISH	0.333
WSB2	PCMTD2	0.316
ELOB	SOCS5	0.288		mutually_exclusive (Q15369)
ELOB	WSB1	0.288		mutually_exclusive (Q15369)
ELOB	SOCS4	0.288
ELOC	SOCS5	0.287		structurally_consistent (dimer)
ELOC	WSB1	0.287		structurally_consistent (dimer)
ELOC	SOCS4	0.287		structurally_consistent (Q93034) structurally_consistent (dimer)
RAB40AL	NEDD8	0.266
TULP4	CISH	0.265
ASB1	ELOC	0.265	0.23	structurally_consistent (dimer)
AMBRA1	RAB40AL	0.264
ASB3	ARIH2	0.228	0.094
PCMTD1	ARIH2	0.224	0.058
LRRC41	NEDD8	0.22	0.036
ASB1	ELOB	0.204	0.19	mutually_exclusive (Q15369)
ISCA1	RNF7	0.173	0.086
ELOC	PCMTD1	0.17	0.126
CISH	ARIH2	0.143
LRRC41	ARIH2	0.141	0.04
LRRC41	ELOC	0.134	0.112
PCMTD2	CISH	0.133
ELOB	PCMTD1	0.128	0.046
LRRC41	ELOB	0.124	0.09
PCMTD2	NEDD8	0.111	0.118
ASB3	AMBRA1	0.102	0.078
ASB13	ELOB	0.096
ASB13	ELOC	0.091
ELOC	PCMTD2	0.087	0.138
NEDD8	PCMTD1	0.075	0.058
AMBRA1	NEDD8	0.07	0.096
RAB40AL	RNF7	0.046
ISCA1	NEDD8	0.041	0.024
ELOB	PCMTD2	0.032	0.182
PCMTD2	ARIH2	0.03	0.092
SOCS3	NEDD8	0.029
AMBRA1	TULP4	0.023
AMBRA1	LRRC28	0.018
LRRC41	AMBRA1	0.017	0.072
AMBRA1	SOCS7	0.015
NUDT6	ELOB	0.015	0.0926666666667
NUDT6	PCMTD1	0.011	0.052
NUDT6	ELOC	0.008	0.128
PCMTD1	RAB40A	0.007
SOCS3	PCMTD1	0.007
AMBRA1	PCMTD1	0.005	0.076
NUDT6	CUL5	0.003	0.08
ISCA1	PCMTD2	0.003	0.086
SOCS3	PCMTD2	0.003
PCMTD2	RAB40A	0.002
AMBRA1	PCMTD2	0.001	0.098

Related Complexes

Genename	Complexes
ASB3	huMAP3_02523.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_11029.1 huMAP3_11858.1 huMAP3_13601.1
RAB40AL	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1 huMAP3_14374.1 huMAP3_14380.1
PCMTD2	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1 huMAP3_14346.1
NUDT6	huMAP3_02435.1 huMAP3_04463.1 huMAP3_04613.1 huMAP3_08903.1 huMAP3_09980.1 huMAP3_10741.1 huMAP3_11182.1 huMAP3_11796.1 huMAP3_12537.1 huMAP3_12976.1 huMAP3_13349.1 huMAP3_14176.1 huMAP3_14746.1
WSB1	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
RAB40C	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
ASB9	huMAP3_00709.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_12854.1
AMBRA1	huMAP3_03188.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09357.1 huMAP3_09980.1 huMAP3_10637.1
SOCS5	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
NEDD8	huMAP3_04750.1 huMAP3_05041.1 huMAP3_05816.1 huMAP3_05894.1 huMAP3_08550.1 huMAP3_08919.1 huMAP3_09779.1 huMAP3_09980.1 huMAP3_14528.1
ASB1	huMAP3_01555.1 huMAP3_02310.1 huMAP3_04750.1 huMAP3_05263.1 huMAP3_05980.1 huMAP3_06706.1 huMAP3_07874.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_12652.1 huMAP3_13601.1
LRRC41	huMAP3_00145.1 huMAP3_02336.1 huMAP3_02504.1 huMAP3_04750.1 huMAP3_05263.1 huMAP3_06952.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_10962.1 huMAP3_13601.1
TULP4	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
WSB2	huMAP3_03772.1 huMAP3_04072.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_06819.1 huMAP3_08860.1 huMAP3_08919.1 huMAP3_09036.1 huMAP3_09980.1 huMAP3_10139.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_13601.1 huMAP3_14626.1
ELOB	huMAP3_03188.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
ELOC	huMAP3_03188.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
SOCS4	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
RNF7	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
SOCS7	huMAP3_03653.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
SOCS6	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
LRRC28	huMAP3_04750.1 huMAP3_05263.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
ASB13	huMAP3_01436.1 huMAP3_04750.1 huMAP3_05263.1 huMAP3_06301.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09431.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
CISH	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
SOCS3	huMAP3_03188.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09357.1 huMAP3_09980.1 huMAP3_10488.1 huMAP3_12329.1
ISCA1	huMAP3_02435.1 huMAP3_04463.1 huMAP3_04613.1 huMAP3_05894.1 huMAP3_08903.1 huMAP3_09980.1 huMAP3_10741.1 huMAP3_13601.1 huMAP3_14176.1
PCMTD1	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1 huMAP3_14346.1
RAB40A	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1 huMAP3_14380.1
SOCS2	huMAP3_04750.1 huMAP3_05263.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
SPSB2	huMAP3_03667.1 huMAP3_04750.1 huMAP3_05768.1 huMAP3_05894.1 huMAP3_06119.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_11027.1 huMAP3_11202.1 huMAP3_13601.1 huMAP3_13839.1
RAB40B	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
ARIH2	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1 huMAP3_14380.1
CUL5	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09980.1

Complex Portal: CPX-16926