hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10623.1

Complex Portal: CPX-24633

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
MT-CYB	Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)	5	UniProt NCBI
COX7A2L	Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7a-related protein) (Cytochrome c oxidase subunit VIIa-related protein) (EB1)	4	UniProt NCBI
COX6C	Cytochrome c oxidase subunit 6C (Cytochrome c oxidase polypeptide VIc)	5	UniProt NCBI
UQCRFS1	Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)]	5	UniProt NCBI
MT-CO3	Cytochrome c oxidase subunit 3 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide III)	5	UniProt NCBI
COX7A2	Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL)	5	UniProt NCBI
UQCRH	Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein)	5	UniProt NCBI
UQCR10	Cytochrome b-c1 complex subunit 9 (Complex III subunit 9) (Complex III subunit X) (Cytochrome c1 non-heme 7 kDa protein) (Ubiquinol-cytochrome c reductase complex 7.2 kDa protein)	5	UniProt NCBI
UQCRQ	Cytochrome b-c1 complex subunit 8 (Complex III subunit 8) (Complex III subunit VIII) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C)	5	UniProt NCBI
COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver) (Cytochrome c oxidase subunit VIA-liver) (COX VIa-L)	5	UniProt NCBI
MT-CO2	Cytochrome c oxidase subunit 2 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide II)	5	UniProt NCBI
PTGES2	Prostaglandin E synthase 2 (EC 5.3.99.3) (Membrane-associated prostaglandin E synthase-2) (mPGE synthase-2) (Microsomal prostaglandin E synthase 2) (mPGES-2) (Prostaglandin-H(2) E-isomerase) [Cleaved into: Prostaglandin E synthase 2 truncated form]	5	UniProt NCBI
UQCRC1	Cytochrome b-c1 complex subunit 1, mitochondrial (Complex III subunit 1) (Core protein I) (Ubiquinol-cytochrome-c reductase complex core protein 1)	5	UniProt NCBI
COX5A	Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)	5	UniProt NCBI
NDUFAF7	Protein arginine methyltransferase NDUFAF7, mitochondrial (EC 2.1.1.320) (NADH dehydrogenase [ubiquinone] complex I, assembly factor 7) (Protein midA homolog)	5	UniProt NCBI
UQCRC2	Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2)	5	UniProt NCBI
LYRM7	Complex III assembly factor LYRM7 (LYR motif-containing protein 7)	5	UniProt NCBI
UNG	Uracil-DNA glycosylase (UDG) (EC 3.2.2.27)	5	UniProt NCBI
COX7C	Cytochrome c oxidase subunit 7C, mitochondrial (Cytochrome c oxidase polypeptide VIIc)	5	UniProt NCBI
UQCRB	Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (QP-C) (Ubiquinol-cytochrome c reductase complex 14 kDa protein)	5	UniProt NCBI
SHISA2	Protein shisa-2 homolog (Transmembrane protein 46)	3	UniProt NCBI
MT-CO1	Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)	5	UniProt NCBI
COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)	5	UniProt NCBI
COX6B1	Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-611105	6.27536262702e-22	0.8	UQCRC1 NDUFAF7 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Respiratory electron transport
KEGG:04260	1.42816193986e-21	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Cardiac muscle contraction
REAC:R-HSA-163200	7.91201131559e-21	0.8	UQCRC1 NDUFAF7 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
GO:0070069	2.4476478307e-20	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	cytochrome complex
WP:WP111	1.02511584904e-19	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Electron transport chain OXPHOS system in mitochondria
REAC:R-HSA-1428517	5.08975826399e-19	0.8	UQCRC1 NDUFAF7 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	The citric acid (TCA) cycle and respiratory electron transport
KEGG:00190	6.54791780711e-19	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Oxidative phosphorylation
KEGG:04714	1.04929979982e-18	0.8	UQCRC1 NDUFAF7 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Thermogenesis
KEGG:04932	2.90241221859e-18	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Non-alcoholic fatty liver disease
WP:WP4396	4.79607308226e-18	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Nonalcoholic fatty liver disease
GO:0070469	8.81281668229e-18	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	respirasome
GO:0005746	8.81281668229e-18	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	mitochondrial respirasome
KEGG:05415	6.13971056721e-17	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Diabetic cardiomyopathy
GO:0045333	8.49989630086e-17	0.8	LYRM7 UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	cellular respiration
WP:WP4921	1.62424646012e-16	0.466666666667	LYRM7 UQCR10 UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CYB	Mitochondrial complex III assembly
KEGG:05208	1.98386428097e-16	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Chemical carcinogenesis - reactive oxygen species
GO:0006119	3.9195342356e-16	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	oxidative phosphorylation
GO:0019646	1.14943938754e-15	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	aerobic electron transport chain
KEGG:05012	1.2459405188e-15	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Parkinson disease
KEGG:05020	1.72249045061e-15	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Prion disease
GO:0098803	1.73323915802e-15	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	respiratory chain complex
GO:0042775	2.57129079936e-15	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	mitochondrial ATP synthesis coupled electron transport
GO:0042773	2.57129079936e-15	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	ATP synthesis coupled electron transport
GO:0015980	2.58653230703e-15	0.8	LYRM7 UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	energy derivation by oxidation of organic compounds
KEGG:05016	5.30553656896e-15	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Huntington disease
GO:0009060	5.60624848655e-15	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	aerobic respiration
GO:0022904	7.70304921067e-15	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	respiratory electron transport chain
GO:0005750	9.00877520842e-15	0.466666666667	MT-CO1 UQCR10 UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CYB	mitochondrial respiratory chain complex III
GO:0045275	9.00877520842e-15	0.466666666667	MT-CO1 UQCR10 UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CYB	respiratory chain complex III
GO:0022900	1.86260858969e-14	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	electron transport chain
KEGG:05014	3.86321176661e-14	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Amyotrophic lateral sclerosis
KEGG:05010	6.59152458666e-14	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Alzheimer disease
GO:0006091	3.83858778744e-13	0.8	LYRM7 UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	generation of precursor metabolites and energy
KEGG:05022	5.81117784466e-13	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	Pathways of neurodegeneration - multiple diseases
GO:0098800	1.11826373647e-12	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	inner mitochondrial membrane protein complex
GO:0006122	8.52814094599e-12	0.4	UQCR10 UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CYB	mitochondrial electron transport, ubiquinol to cytochrome c
GO:0015453	1.17163464163e-11	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	oxidoreduction-driven active transmembrane transporter activity
GO:0031966	1.47283741527e-10	0.8	LYRM7 UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	mitochondrial membrane
GO:0005743	2.86937356259e-10	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	mitochondrial inner membrane
GO:0005740	3.21834526299e-10	0.8	LYRM7 UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	mitochondrial envelope
GO:0019866	5.37458765401e-10	0.733333333333	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	organelle inner membrane
GO:0015078	5.60740077061e-10	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	proton transmembrane transporter activity
GO:0009055	8.68760315162e-10	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	electron transfer activity
GO:0098798	9.36461710511e-10	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	mitochondrial protein-containing complex
GO:0005739	1.02007095385e-09	0.933333333333	LYRM7 UQCRC1 NDUFAF7 UQCRQ PTGES2 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CO1 MT-CYB	mitochondrion
KEGG:01100	4.583008461e-09	0.8	UQCRC1 UQCRQ PTGES2 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CO1 MT-CYB	Metabolic pathways
GO:0015399	8.48100219026e-09	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	primary active transmembrane transporter activity
CORUM:6442	1.71779558077e-08	0.266666666667	COX6C MT-CO3 MT-CO1 MT-CO2	Cytochrome c oxidase, mitochondrial
REAC:R-HSA-1430728	2.91903508316e-08	0.866666666667	UQCRC1 NDUFAF7 UQCRQ PTGES2 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CO1 MT-CYB	Metabolism
GO:0022853	3.26069619168e-08	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	active monoatomic ion transmembrane transporter activity
GO:0008121	3.59167413275e-08	0.266666666667	UQCRH UQCRC1 MT-CYB UQCR10	ubiquinol-cytochrome-c reductase activity
GO:0031975	7.07533459406e-08	0.8	LYRM7 UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	envelope
GO:0031967	7.07533459406e-08	0.8	LYRM7 UQCRC1 UQCRQ MT-CO1 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	organelle envelope
GO:0016679	1.79475545894e-07	0.266666666667	UQCRH UQCRC1 MT-CYB UQCR10	oxidoreductase activity, acting on diphenols and related substances as donors
HP:0003287	2.06397793976e-07	0.466666666667	LYRM7 MT-CO1 MT-CO2 UQCRQ UQCRH MT-CO3 MT-CYB	Abnormality of mitochondrial metabolism
GO:0045277	2.29967832755e-07	0.333333333333	COX6C MT-CO1 UQCRFS1 MT-CO2 MT-CO3	respiratory chain complex IV
GO:0005751	2.29967832755e-07	0.333333333333	COX6C MT-CO1 UQCRFS1 MT-CO2 MT-CO3	mitochondrial respiratory chain complex IV
GO:1990204	3.92741784107e-07	0.466666666667	MT-CO1 UQCR10 UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CYB	oxidoreductase complex
HP:0012103	5.09098427434e-07	0.466666666667	LYRM7 MT-CO1 MT-CO2 UQCRQ UQCRH MT-CO3 MT-CYB	Abnormality of the mitochondrion
HP:0001941	7.22057591997e-07	0.533333333333	LYRM7 MT-CO1 MT-CO2 MT-CYB UQCRQ UQCRH UQCRFS1 MT-CO3	Acidosis
REAC:R-HSA-9707564	7.85999126506e-07	0.333333333333	COX6C MT-CO1 COX7A2L MT-CO2 MT-CO3	Cytoprotection by HMOX1
HP:0001427	1.08227711244e-06	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Mitochondrial inheritance
HP:0004360	1.15928342446e-06	0.533333333333	LYRM7 MT-CO1 MT-CO2 MT-CYB UQCRQ UQCRH UQCRFS1 MT-CO3	Abnormality of acid-base homeostasis
HP:0003200	1.52033558837e-06	0.333333333333	UQCRQ MT-CO1 MT-CYB MT-CO2 MT-CO3	Ragged-red muscle fibers
WP:WP4922	2.82211554015e-06	0.266666666667	COX6C MT-CO3 MT-CO1 MT-CO2	Mitochondrial complex IV assembly
HP:0002401	3.06579125289e-06	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Stroke-like episode
REAC:R-HSA-5628897	3.49812002201e-06	0.333333333333	COX6C MT-CO1 COX7A2L MT-CO2 MT-CO3	TP53 Regulates Metabolic Genes
GO:0022804	3.95897873776e-06	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	active transmembrane transporter activity
HP:0001716	6.98715269064e-06	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Wolff-Parkinson-White syndrome
HP:0004309	1.38147017112e-05	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Ventricular preexcitation
HP:0003128	1.47256005977e-05	0.4	LYRM7 MT-CO1 MT-CO2 MT-CO3 UQCRFS1 MT-CYB	Lactic acidosis
HP:0012707	1.86733656872e-05	0.266666666667	LYRM7 MT-CO3 MT-CO1 MT-CO2	Elevated brain lactate level by MRS
HP:0025045	2.15332038692e-05	0.266666666667	LYRM7 MT-CO3 MT-CO1 MT-CO2	Abnormal brain lactate level by MRS
GO:0022890	2.2067283312e-05	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	inorganic cation transmembrane transporter activity
GO:0004129	2.55415843789e-05	0.266666666667	MT-CO1 COX7A2L MT-CO2 MT-CO3	cytochrome-c oxidase activity
GO:0016675	2.55415843789e-05	0.266666666667	MT-CO1 COX7A2L MT-CO2 MT-CO3	oxidoreductase activity, acting on a heme group of donors
GO:0016491	2.59052892179e-05	0.6	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	oxidoreductase activity
HPA:0241103	2.67805703662e-05	0.6	LYRM7 PTGES2 MT-CO2 COX6C UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CO1	heart muscle; cardiomyocytes[High]
HP:0002151	2.71027023977e-05	0.4	LYRM7 MT-CO1 MT-CO2 MT-CO3 UQCRH UQCRQ	Increased serum lactate
GO:0008324	4.3133182865e-05	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	monoatomic cation transmembrane transporter activity
HP:0000408	6.42780875128e-05	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Progressive sensorineural hearing impairment
GO:0006123	6.48975026044e-05	0.266666666667	COX6C MT-CO3 MT-CO1 MT-CO2	mitochondrial electron transport, cytochrome c to oxygen
GO:1902495	9.52620252691e-05	0.466666666667	MT-CO1 UQCR10 UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CYB	transmembrane transporter complex
HP:0012377	9.62109054887e-05	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Hemianopia
GO:0015318	9.70852540113e-05	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	inorganic molecular entity transmembrane transporter activity
GO:0098796	0.000108071564716	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	membrane protein complex
HP:0007327	0.000116123723148	0.2	MT-CO1 MT-CO3 MT-CO2	Mixed demyelinating and axonal polyneuropathy
HP:0001730	0.000126989624977	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Progressive hearing impairment
HP:0002572	0.000138718902694	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Episodic vomiting
HP:0005157	0.000159571763997	0.2	MT-CO1 MT-CO3 MT-CO2	Concentric hypertrophic cardiomyopathy
GO:1990351	0.000164847022854	0.466666666667	MT-CO1 UQCR10 UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CYB	transporter complex
GO:0015075	0.000172435720005	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	monoatomic ion transmembrane transporter activity
HP:0012766	0.000212631290555	0.2	MT-CO1 MT-CO3 MT-CO2	Widened cerebral subarachnoid space
HP:0000576	0.000212631290555	0.2	MT-CO1 MT-CYB MT-CO3	Centrocecal scotoma
HP:0012705	0.000226914367315	0.266666666667	LYRM7 MT-CO3 MT-CO1 MT-CO2	Abnormal metabolic brain imaging by MRS
REAC:R-HSA-9711123	0.000236683088638	0.333333333333	COX6C MT-CO1 COX7A2L MT-CO2 MT-CO3	Cellular response to chemical stress
HP:0003737	0.00024491968581	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Mitochondrial myopathy
WP:WP5380	0.000250825872505	0.266666666667	COX6C MT-CO3 MT-CO1 MT-CO2	5q35 copy number variation
HP:0007067	0.000276250400492	0.2	MT-CO1 MT-CO3 MT-CO2	Distal peripheral sensory neuropathy
HP:0007159	0.000276250400492	0.2	MT-CO1 MT-CO3 MT-CO2	Fluctuations in consciousness
GO:0031090	0.000344554461797	0.866666666667	LYRM7 UQCRC1 UQCRQ PTGES2 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CO1 MT-CYB	organelle membrane
HPA:0360053	0.000348427490789	0.6	LYRM7 PTGES2 MT-CO2 COX6C UQCRQ MT-CO1 UQCRC1 UQCRFS1 MT-CYB	parathyroid gland; glandular cells[High]
HP:0000544	0.00035140911792	0.266666666667	LYRM7 MT-CO3 MT-CO1 MT-CO2	External ophthalmoplegia
HP:0025268	0.000438947971843	0.2	MT-CO1 MT-CO3 MT-CO2	Stuttering
HP:0100027	0.000438947971843	0.2	MT-CO1 MT-CO3 MT-CO2	Recurrent pancreatitis
HP:0011017	0.000463148271283	0.466666666667	LYRM7 MT-CO1 MT-CO2 UQCRQ UQCRH MT-CO3 MT-CYB	Abnormal cellular physiology
HP:0008619	0.000520862325813	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Bilateral sensorineural hearing impairment
HP:0012429	0.000539910849948	0.2	MT-CO1 MT-CO3 MT-CO2	Aplasia/Hypoplasia of the cerebral white matter
HP:0025354	0.000631287470941	0.466666666667	LYRM7 MT-CO1 MT-CO2 UQCRQ UQCRH MT-CO3 MT-CYB	Abnormal cellular phenotype
HP:0200125	0.000655202151928	0.2	MT-CO1 MT-CYB MT-CO3	Mitochondrial respiratory chain defects
HP:0001733	0.000744798354237	0.266666666667	UQCRH MT-CO3 MT-CO1 MT-CO2	Pancreatitis
HP:0003812	0.000744798354237	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Phenotypic variability
HP:0003828	0.000744798354237	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Variable expressivity
HP:0001345	0.00109639830438	0.2	MT-CO1 MT-CO3 MT-CO2	Psychotic mentation
HPA:0271133	0.00111410251292	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	kidney; distal tubules[High]
HP:0003800	0.00120577582672	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Muscle abnormality related to mitochondrial dysfunction
HP:0004372	0.00136260379198	0.333333333333	LYRM7 MT-CO1 MT-CYB MT-CO2 MT-CO3	Reduced consciousness
HP:0001269	0.00146747680669	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Hemiparesis
HP:0002331	0.00170011826836	0.2	MT-CO1 MT-CO3 MT-CO2	Recurrent paroxysmal headache
HP:0000602	0.00181613266739	0.333333333333	LYRM7 MT-CO1 MT-CYB MT-CO2 MT-CO3	Ophthalmoplegia
HP:0007763	0.00194179523094	0.2	MT-CO1 MT-CYB MT-CO3	Retinal telangiectasia
HP:0001712	0.00220855671689	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Left ventricular hypertrophy
HP:0010794	0.00249132827704	0.2	MT-CO1 MT-CO3 MT-CO2	Impaired visuospatial constructive cognition
HP:0030085	0.00261456055522	0.266666666667	LYRM7 MT-CO3 MT-CO1 MT-CO2	Abnormal CSF lactate concentration
HP:0002490	0.00261456055522	0.266666666667	LYRM7 MT-CO3 MT-CO1 MT-CO2	Increased CSF lactate
HP:0001045	0.00280101747395	0.2	MT-CO1 MT-CO3 MT-CO2	Vitiligo
HP:0004303	0.00282941911902	0.333333333333	UQCRQ MT-CO1 MT-CYB MT-CO2 MT-CO3	Abnormal muscle fiber morphology
HP:0004370	0.00326183551815	0.4	MT-CO1 MT-CO2 MT-CO3 UQCRH UQCRFS1 MT-CYB	Abnormality of temperature regulation
HP:0000597	0.00348029049205	0.333333333333	LYRM7 MT-CO1 MT-CYB MT-CO2 MT-CO3	Ophthalmoparesis
HP:0004389	0.00349480667591	0.2	MT-CO1 MT-CO3 MT-CO2	Intestinal pseudo-obstruction
HP:0000590	0.00349480667591	0.2	MT-CO1 MT-CO3 MT-CO2	Progressive external ophthalmoplegia
HP:0007924	0.00429387068757	0.2	MT-CO1 MT-CYB MT-CO3	Slow decrease in visual acuity
REAC:R-HSA-3700989	0.004771951065	0.333333333333	COX6C MT-CO1 COX7A2L MT-CO2 MT-CO3	Transcriptional Regulation by TP53
HP:0001711	0.00498386535344	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Abnormal left ventricle morphology
HPA:0090183	0.00530898247096	0.4	LYRM7 MT-CO1 MT-CO2 COX6C UQCRQ UQCRH	cerebellum; cells in granular layer[High]
HP:0005162	0.00552714476514	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Abnormal left ventricular function
GO:0022857	0.00580921893687	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	transmembrane transporter activity
HP:0007302	0.00623674771082	0.2	MT-CO1 MT-CO3 MT-CO2	Bipolar affective disorder
HP:0000829	0.00623674771082	0.2	MT-CO1 MT-CO3 MT-CO2	Hypoparathyroidism
HP:0001298	0.00673698982716	0.333333333333	LYRM7 MT-CO1 MT-CYB MT-CO2 MT-CO3	Encephalopathy
HP:0002076	0.00696446920409	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Migraine
WP:WP4919	0.00716764668608	0.133333333333	MT-CO1 MT-CO2	Neuroinflammation
HP:0003546	0.00719034985144	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Exercise intolerance
HP:0000622	0.00739493145726	0.2	MT-CO1 MT-CYB MT-CO3	Blurred vision
HP:0000519	0.00765832926472	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Developmental cataract
HP:0031546	0.00790059230054	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Cardiac conduction abnormality
HP:0011924	0.00802383527375	0.2	UQCRH UQCRQ LYRM7	Decreased activity of mitochondrial complex III
HP:0008316	0.00868713170593	0.2	MT-CO1 MT-CO3 MT-CO2	Abnormal mitochondria in muscle tissue
HP:0000751	0.00868713170593	0.2	MT-CO1 MT-CO3 MT-CO2	Personality changes
HP:0012704	0.00868713170593	0.2	MT-CO1 MT-CO3 MT-CO2	Widened subarachnoid space
HP:0002013	0.00915441900189	0.333333333333	UQCRH MT-CO1 MT-CYB MT-CO2 MT-CO3	Vomiting
HP:0025454	0.00919797362166	0.266666666667	LYRM7 MT-CO3 MT-CO1 MT-CO2	Abnormal CSF metabolite concentration
HP:0000603	0.00938570640907	0.2	MT-CO1 MT-CYB MT-CO3	Central scotoma
HP:0030872	0.00947525460656	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Abnormal cardiac ventricular function
HP:0410263	0.0103442513287	0.266666666667	LYRM7 MT-CO3 MT-CO1 MT-CO2	Brain imaging abnormality
HP:0001714	0.0103442513287	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Ventricular hypertrophy
HP:0002135	0.0108922219338	0.2	MT-CO1 MT-CO3 MT-CO2	Basal ganglia calcification
HP:0000745	0.0111438373738	0.4	LYRM7 MT-CO1 MT-CO2 MT-CYB UQCRC1 MT-CO3	Diminished motivation
WP:000000	0.0115632200884	0.933333333333	LYRM7 UQCRC1 NDUFAF7 UQCRQ PTGES2 MT-CO2 COX7A2L COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CO1 MT-CYB	WIKIPATHWAYS
HPA:0290403	0.011856542586	0.4	LYRM7 MT-CO2 COX6C UQCRQ UQCRC1 UQCRFS1	liver; hepatocytes[High]
HP:5200275	0.0119859324781	0.4	LYRM7 MT-CO1 MT-CO2 MT-CYB UQCRC1 MT-CO3	Abnormal motivation
HPA:0030433	0.012028358343	0.2	MT-CO1 UQCRFS1 MT-CO2	appendix; germinal center cells[High]
HP:0100704	0.0122573313936	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Cerebral visual impairment
HP:0012091	0.0125999141222	0.266666666667	UQCRH MT-CO3 MT-CO1 MT-CO2	Abnormality of pancreas physiology
HP:0002922	0.0134385936527	0.2	MT-CO1 MT-CO3 MT-CO2	Increased CSF protein concentration
GO:1902494	0.0139038086596	0.666666666667	UQCRC1 UQCRQ MT-CO1 MT-CO2 COX6C MT-CO3 UQCR10 UQCRH UQCRFS1 MT-CYB	catalytic complex
GO:0005215	0.0139177699031	0.533333333333	UQCRC1 MT-CO1 MT-CO2 COX7A2L MT-CO3 UQCR10 UQCRH MT-CYB	transporter activity
HPA:0271132	0.0148280154625	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	kidney; distal tubules[>=Medium]
HPA:0271111	0.0152261714989	0.266666666667	COX6C UQCRFS1 MT-CO1 UQCRC1	kidney; bowman's capsule[>=Low]
HP:0000114	0.0153374414385	0.2	MT-CO1 MT-CO3 MT-CO2	Proximal tubulopathy
HP:0025456	0.0153374414385	0.2	MT-CO1 MT-CO3 MT-CO2	Abnormal CSF protein concentration
HP:0001297	0.0156011628905	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Stroke
HPA:0271142	0.0160091879402	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	kidney; proximal tubules (cell body)[>=Medium]
HP:0100651	0.0185049883485	0.2	MT-CO1 MT-CO3 MT-CO2	Type I diabetes mellitus
HP:0001945	0.0187453432338	0.333333333333	UQCRH MT-CO1 MT-CYB MT-CO2 MT-CO3	Fever
HPA:0470182	0.0201754514161	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	skin 2; cells in granular layer[>=Medium]
HPA:0310433	0.0202746765253	0.4	LYRM7 MT-CO1 MT-CO2 COX6C UQCRC1 UQCRFS1	lymph node; germinal center cells[High]
HP:0012841	0.0208396068145	0.2	MT-CO1 MT-CYB MT-CO3	Retinal vascular tortuosity
HP:0002174	0.0220763683613	0.2	MT-CO1 MT-CYB MT-CO3	Postural tremor
HP:0012544	0.0228738874103	0.133333333333	MT-CO1 MT-CO3	Elevated circulating aldolase concentration
HP:0003652	0.0228738874103	0.133333333333	MT-CO1 MT-CO3	Recurrent myoglobinuria
HP:0004308	0.0242486362315	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Ventricular arrhythmia
HP:0000097	0.0246930674642	0.2	MT-CO1 MT-CO3 MT-CO2	Focal segmental glomerulosclerosis
HP:0001271	0.0260747069276	0.2	UQCRC1 MT-CYB MT-CO3	Polyneuropathy
HP:0011767	0.0289888038748	0.2	MT-CO1 MT-CO3 MT-CO2	Abnormality of the parathyroid physiology
HP:0012795	0.0297966905645	0.4	LYRM7 MT-CO1 MT-CO2 MT-CO3 UQCRFS1 MT-CYB	Abnormal optic disc morphology
HP:0030234	0.0304804305825	0.133333333333	MT-CO1 MT-CO3	Highly elevated creatine kinase
HPA:0430053	0.0306201290682	0.466666666667	MT-CO1 MT-CO2 COX6C UQCRQ UQCRH UQCRC1 UQCRFS1	seminal vesicle; glandular cells[High]
HPA:0530722	0.0307079753377	0.6	LYRM7 PTGES2 MT-CO2 COX6C MT-CYB UQCRC1 UQCRH UQCRFS1 MT-CO1	spleen; cells in white pulp[>=Medium]
HPA:0241102	0.0331891292521	0.733333333333	LYRM7 PTGES2 MT-CO2 COX6C MT-CYB MT-CO3 UQCRC1 UQCRH UQCRFS1 MT-CO1 UQCRQ	heart muscle; cardiomyocytes[>=Medium]
HP:0012337	0.0345869290394	0.533333333333	LYRM7 MT-CO1 MT-CO2 MT-CYB UQCRQ UQCRH UQCRFS1 MT-CO3	Abnormal homeostasis
HP:0000726	0.0375213832059	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Dementia
HP:0001112	0.0391658859752	0.133333333333	MT-CYB MT-CO3	Leber optic atrophy
HPA:0360052	0.0412465388516	0.733333333333	LYRM7 PTGES2 MT-CO2 COX6C MT-CYB MT-CO3 UQCRC1 UQCRH UQCRFS1 MT-CO1 UQCRQ	parathyroid gland; glandular cells[>=Medium]
HPA:0471472	0.041821522969	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	skin 2; lymphocytes[>=Medium]
HPA:0470672	0.0421413491005	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	skin 2; melanocytes[>=Medium]
HPA:0271131	0.0427866315125	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	kidney; distal tubules[>=Low]
HP:0000828	0.0447570458207	0.2	MT-CO1 MT-CO3 MT-CO2	Abnormality of the parathyroid gland
HP:0000575	0.0447570458207	0.2	MT-CO1 MT-CYB MT-CO3	Scotoma
HP:0004374	0.0449713160241	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Hemiplegia/hemiparesis
HP:0009830	0.0458992907679	0.333333333333	UQCRC1 MT-CO1 MT-CYB MT-CO2 MT-CO3	Peripheral neuropathy
HPA:0471462	0.0464723849611	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	skin 2; langerhans cells[>=Medium]
HP:0000572	0.0467641268856	0.266666666667	MT-CO1 MT-CYB MT-CO2 MT-CO3	Visual loss
HPA:0351182	0.0486694073855	0.666666666667	LYRM7 PTGES2 MT-CO2 COX6C UQCRQ UQCRC1 UQCRH UQCRFS1 MT-CO1 MT-CYB	pancreas; pancreatic endocrine cells[>=Medium]
HP:0007768	0.0489283265382	0.133333333333	MT-CYB MT-CO3	Central retinal vessel vascular tortuosity
HP:0000631	0.0489283265382	0.133333333333	MT-CYB MT-CO3	Retinal arterial tortuosity
HPA:0271141	0.0496651010791	0.333333333333	COX6C UQCRC1 UQCRFS1 MT-CO1 MT-CO2	kidney; proximal tubules (cell body)[>=Low]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
COX5A	COX4I1	0.999	0.984	structurally_consistent (dimer)
MT-CO2	COX4I1	0.999	0.89	structurally_consistent (dimer)
UQCRB	UQCRC1	0.999	0.986
UQCRC2	UQCRC1	0.999	0.958	structurally_consistent (dimer)
UQCRC2	UQCRQ	0.999	0.96	structurally_consistent (P47985) structurally_consistent (dimer)
UQCRC2	UQCRFS1	0.999	0.966	structurally_consistent (dimer)
LYRM7	UQCRFS1	0.998	0.07
UQCRC2	MT-CO2	0.998	0.83	structurally_consistent (P13073)
UQCRQ	PTGES2	0.998	0.11
UQCRQ	UQCRC1	0.998	0.962
UQCRFS1	UQCRC1	0.997	0.988	structurally_consistent (dimer)
UQCRC2	UQCRB	0.997	0.992	structurally_consistent (dimer)
UQCRH	UQCRC1	0.997	0.876
UQCRC2	COX4I1	0.997	0.842	structurally_consistent (dimer)
UQCRH	UQCR10	0.997	0.932	structurally_consistent (P00156)
UQCRB	UQCRQ	0.996	0.992	structurally_consistent (P22695) structurally_consistent (dimer)
UQCRH	UQCRQ	0.995	0.612	structurally_consistent (P00156)
COX7A2L	UQCRQ	0.995	0.726
MT-CYB	UQCRQ	0.995	0.77	structurally_consistent (dimer)
UQCRH	COX7A2L	0.995	0.21
UQCRC1	COX4I1	0.995	0.904
SHISA2	PTGES2	0.994
UQCR10	UQCRQ	0.994	0.766
UQCRB	COX6C	0.994	0.944
COX7A2L	COX5A	0.993	0.686
UQCRB	PTGES2	0.993	0.122	structurally_consistent (P00156) structurally_consistent (dimer)
MT-CO3	COX4I1	0.992	0.774	structurally_consistent (P00395) structurally_consistent (dimer)
UQCRQ	COX6C	0.992	0.936	mutually_exclusive (P00403)
UQCRFS1	PTGES2	0.992	0.126
UQCRH	UQCRB	0.992	0.964	structurally_consistent (P00156) structurally_consistent (dimer)
UQCRFS1	UQCRQ	0.992	0.986	structurally_consistent (dimer)
NDUFAF7	UQCRFS1	0.992	0.118	structurally_consistent (dimer)
UNG	UQCRFS1	0.991	0.084
PTGES2	UQCRC1	0.99	0.228
COX6C	COX6A1	0.99	0.602
COX7A2L	UQCRB	0.989	0.882
UQCR10	UQCRC1	0.989	0.758
UQCRC2	PTGES2	0.988	0.296	structurally_consistent (dimer)
UQCRH	MT-CYB	0.988	0.194	structurally_consistent (dimer)
COX7A2	COX6B1	0.988	0.952	structurally_consistent (P00414)
UQCRC2	MT-CO3	0.986	0.598
COX6B1	COX6A1	0.986	0.766
UQCRFS1	UQCRB	0.985	0.98
MT-CYB	PTGES2	0.985	0.276	structurally_consistent (dimer)
UQCRFS1	COX4I1	0.985	0.908	mutually_exclusive (P22695) structurally_consistent (dimer)
COX6B1	COX4I1	0.984	0.83	structurally_consistent (P00403) structurally_consistent (dimer)
UQCRC2	UQCR10	0.984	0.58
COX7A2	COX4I1	0.984	0.716	structurally_consistent (P00403)
COX7A2L	MT-CYB	0.983	0.652
MT-CYB	UQCRB	0.981	0.814	structurally_consistent (Q9H7Z7) structurally_consistent (dimer)
MT-CO3	COX6A1	0.98	0.454
UQCRC2	COX7A2L	0.979	0.828
COX7A2L	UQCRC1	0.979	0.584
UQCRH	UQCRC2	0.978	0.686	structurally_consistent (P14927)
COX6C	COX4I1	0.975	0.96	structurally_consistent (dimer)
UQCRC2	COX6A1	0.974	0.526	structurally_consistent (P47985)
COX7A2L	PTGES2	0.973	0.06
MT-CO1	UQCRQ	0.972	0.492	mutually_exclusive (P00403)
COX7A2L	COX6A1	0.972	0.784
COX7A2	NDUFAF7	0.969	0.0963339882122
MT-CO1	COX4I1	0.968	0.776	structurally_consistent (dimer)
MT-CO3	MT-CO1	0.967	0.52	structurally_consistent (dimer)
COX5A	COX6C	0.967	0.904
COX7A2L	MT-CO1	0.967	0.424
MT-CO1	COX6C	0.967	0.908
MT-CYB	UQCR10	0.966	0.612	structurally_consistent (dimer)
COX6A1	COX4I1	0.966	0.672	structurally_consistent (P00395)
COX7A2L	COX6C	0.965	0.834
UQCRB	UQCR10	0.965	0.914	structurally_consistent (P00156)
MT-CO1	COX6A1	0.963	0.632	structurally_consistent (dimer)
MT-CO1	UQCRB	0.961	0.898
COX6C	COX7C	0.96	0.924
COX7A2	UQCRFS1	0.958	0.89
UQCRC2	MT-CYB	0.958	0.78
UQCRH	MT-CO3	0.958	0.222
UQCRQ	COX6B1	0.958	0.58	structurally_consistent (P47985)
COX7A2L	COX6B1	0.957	0.696
COX7A2L	COX4I1	0.957	0.814
UQCRC1	COX6A1	0.955	0.466	structurally_consistent (P47985)
COX6B1	UQCRC1	0.953	0.782	structurally_consistent (P47985)
UQCRB	COX6A1	0.953	0.836
COX7A2L	MT-CO3	0.952	0.198
UQCRFS1	UQCR10	0.952	0.846	structurally_consistent (P00156)
UQCRQ	COX6A1	0.952	0.756
UQCRFS1	MT-CYB	0.951	0.842	structurally_consistent (dimer)
MT-CO2	COX6A1	0.951	0.712
MT-CO1	COX5A	0.95	0.616
COX7A2	COX6A1	0.949	0.652
COX5A	UQCRC1	0.947	0.888
COX7C	UQCRC1	0.945	0.954	mutually_exclusive (P22695)
UQCRC2	COX7C	0.944	0.848	structurally_consistent (dimer)
MT-CO2	COX7A2	0.944	0.822	structurally_consistent (dimer)
MT-CYB	UQCRC1	0.944	0.762
UQCRB	COX4I1	0.943	0.936	structurally_consistent (P22695)
COX7C	COX4I1	0.94	0.814	mutually_exclusive (P22695)
MT-CO3	COX6C	0.939	0.824	structurally_consistent (P13073)
COX5A	COX7C	0.934	0.968
UQCRQ	COX4I1	0.931	0.82
COX5A	UQCRQ	0.93	0.792
UQCRC2	COX5A	0.929	0.864	structurally_consistent (P13073)
MT-CO1	UQCRC1	0.928	0.836
COX6C	UQCRC1	0.927	0.95
COX5A	COX6A1	0.927	0.62
COX7A2L	UQCR10	0.925	0.53
UQCRC2	COX6C	0.923	0.908	structurally_consistent (P13073)
PTGES2	COX4I1	0.921	0.154	mutually_exclusive (P22695)
COX5A	UQCRFS1	0.919	0.884	mutually_exclusive (P13073)
COX6B1	COX6C	0.917	0.91	structurally_consistent (P00403)
LYRM7	UQCRQ	0.917	0.018
MT-CO3	COX7A2	0.915	0.688	structurally_consistent (dimer)
MT-CO3	COX7C	0.912	0.646
COX7A2	COX7C	0.909	0.9536	structurally_consistent (dimer)
MT-CO3	UQCRC1	0.903	0.618
MT-CO3	UQCRQ	0.902	0.694
COX7A2L	UQCRFS1	0.899	0.82
MT-CO3	UQCR10	0.89	0.57
COX7A2	COX6C	0.88	0.848
MT-CO2	COX7C	0.876	0.82
COX5A	UQCRB	0.875	0.856
UQCRB	COX6B1	0.874	0.864
MT-CO1	COX6B1	0.873	0.786	structurally_consistent (P13073)
MT-CO3	COX6B1	0.871	0.52	structurally_consistent (P13073) structurally_consistent (dimer)
UQCR10	COX4I1	0.864	0.624
COX5A	COX7A2	0.862	0.906	structurally_consistent (P00414)
UQCR10	PTGES2	0.858	0.314	structurally_consistent (P00156)
UQCRH	COX7C	0.846	0.83
MT-CO2	COX5A	0.843	0.872
UQCRFS1	COX6B1	0.842	0.71	structurally_consistent (P13073) structurally_consistent (dimer)
COX7A2L	COX7A2	0.838	0.686
MT-CO3	COX5A	0.824	0.732	structurally_consistent (dimer)
MT-CO1	MT-CYB	0.824	0.734
MT-CO3	UQCRB	0.823	0.666
UQCRC2	COX6B1	0.815	0.736
LYRM7	COX4I1	0.807	0.114
MT-CO2	UQCRC1	0.8	0.876
LYRM7	UNG	0.78	0.016
MT-CO2	UQCR10	0.777	0.226
LYRM7	UQCRC1	0.754	0.25
UQCR10	COX6B1	0.751	0.326
MT-CO1	UQCR10	0.749	0.364
UQCRFS1	COX6A1	0.748	0.674	structurally_consistent (dimer)
UQCRC2	MT-CO1	0.746	0.802
MT-CO2	COX7A2L	0.74	0.69
UQCR10	COX6C	0.72	0.264
COX7A2	UQCRC1	0.676	0.802
MT-CYB	COX6B1	0.676	0.448	mutually_exclusive (P47985)
UQCRB	SHISA2	0.661
COX5A	UQCR10	0.66	0.542
NDUFAF7	UNG	0.659	0.042
LYRM7	UQCRB	0.639	0.02
MT-CO2	MT-CO3	0.638	0.692
LYRM7	NDUFAF7	0.629	0.312
MT-CO1	COX7A2	0.622	0.814
LYRM7	UQCRC2	0.602	0.284
LYRM7	COX5A	0.578	0.11
COX7A2	UQCRQ	0.562	0.85
UQCRH	MT-CO2	0.561	0.36
MT-CO2	COX6B1	0.555	0.842	structurally_consistent (dimer)
UQCRH	UQCRFS1	0.553	0.846
UQCR10	COX6A1	0.523	0.272
UQCRH	COX6B1	0.5	0.482
MT-CO1	COX7C	0.474	0.88	structurally_consistent (dimer)
NDUFAF7	COX4I1	0.451	0.162
MT-CYB	COX4I1	0.444	0.648
COX7A2	UNG	0.413	0.056
UQCRH	COX7A2	0.407	0.582
COX5A	UNG	0.394	0.206
UQCRC2	COX7A2	0.393	0.812	structurally_consistent (P15954)
COX5A	COX6B1	0.389	0.856	structurally_consistent (P13073)
UQCRH	COX5A	0.388	0.752
COX7A2	UQCRB	0.386	0.972
UNG	UQCRC1	0.379	0.138
LYRM7	COX7A2	0.374	0.07
UQCRH	COX4I1	0.353	0.812
NDUFAF7	UQCRC1	0.351	0.054
UQCRH	MT-CO1	0.342	0.21
COX6B1	COX7C	0.335	0.912
MT-CO2	MT-CO1	0.333	0.856	structurally_consistent (dimer)
UQCR10	COX7C	0.333	0.744
UQCRH	COX6C	0.305	0.342
MT-CO1	PTGES2	0.291	0.156
MT-CO2	UQCRQ	0.29	0.876	structurally_consistent (dimer)
COX5A	NDUFAF7	0.289	0.162
UQCRH	PTGES2	0.284	0.214
UQCRB	COX7C	0.274	0.822
MT-CO1	UQCRFS1	0.246	0.69	mutually_exclusive (P13073)
UNG	COX4I1	0.244	0.176
UNG	PTGES2	0.227	0.06
COX6C	PTGES2	0.225	0.07
NDUFAF7	UQCRB	0.223	0.136
COX5A	PTGES2	0.219	0.184
COX7A2	UQCR10	0.21	0.3
UQCRFS1	COX7C	0.18	0.918	mutually_exclusive (P22695)
MT-CO2	UQCRB	0.177	0.87	mutually_exclusive (O14949)
COX7A2L	COX7C	0.169	0.768
LYRM7	PTGES2	0.163	0.036
MT-CYB	COX6C	0.157	0.624
NDUFAF7	COX6B1	0.153	0.174
UNG	UQCRB	0.153	0.056
UQCRC2	UNG	0.151	0.106
MT-CO2	PTGES2	0.149	0.142
LYRM7	COX7A2L	0.145	0.022
MT-CO3	MT-CYB	0.133	0.578
COX6B1	PTGES2	0.133	0.084
MT-CO2	UQCRFS1	0.131	0.7	mutually_exclusive (P14854)
MT-CO2	COX6C	0.127	0.974	structurally_consistent (dimer)
COX7A2	PTGES2	0.12	0.0883339882122
UNG	UQCRQ	0.115	0.038
MT-CO3	UQCRFS1	0.107	0.536
LYRM7	MT-CYB	0.103	0.086
COX5A	MT-CYB	0.097	0.448
UQCRQ	COX7C	0.087	0.862
LYRM7	COX6A1	0.085	0.084
COX7A2L	NDUFAF7	0.081	0.024
NDUFAF7	PTGES2	0.081	0.146
UNG	MT-CYB	0.076	0.066
COX7A2L	UNG	0.076	0.022
LYRM7	MT-CO1	0.076	0.02
UQCRFS1	COX6C	0.071	0.764
LYRM7	UQCR10	0.071	0.044
LYRM7	COX6B1	0.068	0.046
MT-CO3	NDUFAF7	0.064	0.084
COX7A2	MT-CYB	0.063	0.44
UQCRH	COX6A1	0.063	0.186
NDUFAF7	COX6A1	0.058	0.066	structurally_consistent (P47985)
MT-CO2	MT-CYB	0.058	0.528	mutually_exclusive (O14949)
NDUFAF7	COX6C	0.055	0.024
MT-CO2	NDUFAF7	0.055	0.038
UQCRH	NDUFAF7	0.054	0.186
LYRM7	UQCRH	0.051	0.086
UQCRH	UNG	0.05	0.046
NDUFAF7	MT-CYB	0.045	0.08
LYRM7	MT-CO3	0.045	0.06
LYRM7	COX6C	0.043	0.09
UQCRC2	NDUFAF7	0.041	0.094
NDUFAF7	UQCRQ	0.039	0.034	structurally_consistent (P47985)
UNG	UQCR10	0.035	0.022
MT-CO3	PTGES2	0.022	0.086
COX5A	SHISA2	0.018
NDUFAF7	UQCR10	0.016	0.112
SHISA2	COX4I1	0.015
MT-CO1	NDUFAF7	0.013	0.022
SHISA2	UQCRC1	0.012
LYRM7	MT-CO2	0.011	0.042
PTGES2	COX6A1	0.01	0.22
MT-CO2	SHISA2	0.008
UQCRC2	SHISA2	0.004
UQCRFS1	SHISA2	0.003

Related Complexes

Genename	Complexes
MT-CYB	huMAP3_02983.1 huMAP3_06133.1 huMAP3_08223.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
COX7A2L	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
COX6C	huMAP3_04820.1 huMAP3_07696.1 huMAP3_10623.1 huMAP3_10718.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
UQCRFS1	huMAP3_01826.1 huMAP3_04728.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_09982.1 huMAP3_10294.1 huMAP3_10458.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14018.1 huMAP3_14580.1
MT-CO3	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07840.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1
COX7A2	huMAP3_01629.1 huMAP3_03863.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_10024.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
UQCRH	huMAP3_00773.1 huMAP3_07497.1 huMAP3_08223.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_14574.1
UQCR10	huMAP3_02983.1 huMAP3_07497.1 huMAP3_08223.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12457.1
UQCRQ	huMAP3_02983.1 huMAP3_05463.1 huMAP3_06133.1 huMAP3_07069.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
COX6A1	huMAP3_07005.1 huMAP3_08546.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
MT-CO2	huMAP3_00773.1 huMAP3_05665.1 huMAP3_07005.1 huMAP3_08024.1 huMAP3_08311.1 huMAP3_08386.1 huMAP3_09906.1 huMAP3_10623.1
PTGES2	huMAP3_05353.1 huMAP3_08546.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_12970.1 huMAP3_14560.1 huMAP3_14580.1
UQCRC1	huMAP3_06133.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_09982.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14018.1 huMAP3_14560.1 huMAP3_14580.1
COX5A	huMAP3_01464.1 huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
NDUFAF7	huMAP3_01629.1 huMAP3_01826.1 huMAP3_07021.1 huMAP3_07227.1 huMAP3_07890.1 huMAP3_10024.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_13468.1 huMAP3_14910.1
UQCRC2	huMAP3_00773.1 huMAP3_06247.1 huMAP3_07245.1 huMAP3_07497.1 huMAP3_08223.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12457.1 huMAP3_12621.1
LYRM7	huMAP3_00475.1 huMAP3_01826.1 huMAP3_04728.1 huMAP3_06034.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_09941.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14580.1
UNG	huMAP3_01826.1 huMAP3_03561.1 huMAP3_04728.1 huMAP3_05671.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_08389.1 huMAP3_09058.1 huMAP3_10294.1 huMAP3_10341.1 huMAP3_10623.1 huMAP3_10642.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12510.1 huMAP3_14580.1
COX7C	huMAP3_04820.1 huMAP3_07696.1 huMAP3_10623.1 huMAP3_10718.1 huMAP3_11232.1 huMAP3_12457.1
UQCRB	huMAP3_02983.1 huMAP3_06133.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
SHISA2	huMAP3_03681.1 huMAP3_05353.1 huMAP3_10623.1
MT-CO1	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07696.1 huMAP3_07840.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1
COX4I1	huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_10725.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14580.1
COX6B1	huMAP3_03863.1 huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10024.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_13252.1 huMAP3_14580.1 huMAP3_14899.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10623.1

Complex Portal: CPX-24633