hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10623.1

Complex Portal: CPX-24633

Confidence: Medium High

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Genename	Protein Name	Uniprot Annotation Score	Links
COX4I1	Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)	5	UniProt NCBI
COX5A	Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)	5	UniProt NCBI
COX6A1	Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver) (Cytochrome c oxidase subunit VIA-liver) (COX VIa-L)	5	UniProt NCBI
COX6B1	Cytochrome c oxidase subunit 6B1 (Cytochrome c oxidase subunit VIb isoform 1) (COX VIb-1)	5	UniProt NCBI
COX6C	Cytochrome c oxidase subunit 6C (Cytochrome c oxidase polypeptide VIc)	5	UniProt NCBI
COX7A2	Cytochrome c oxidase subunit 7A2, mitochondrial (Cytochrome c oxidase subunit VIIa-liver/heart) (Cytochrome c oxidase subunit VIIa-L) (Cytochrome c oxidase subunit VIIaL)	5	UniProt NCBI
COX7A2L	Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7a-related protein) (Cytochrome c oxidase subunit VIIa-related protein) (EB1)	4	UniProt NCBI
COX7C	Cytochrome c oxidase subunit 7C, mitochondrial (Cytochrome c oxidase polypeptide VIIc)	5	UniProt NCBI
LYRM7	Complex III assembly factor LYRM7 (LYR motif-containing protein 7)	5	UniProt NCBI
MT-CO1	Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)	5	UniProt NCBI

Showing 1 to 10 of 24 entries

Enrichments

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-611105	6.27536262702e-22	0.8	MT-CO3 NDUFAF7 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	Respiratory electron transport
KEGG:04260	1.42816193986e-21	0.733333333333	MT-CO3 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	Cardiac muscle contraction
REAC:R-HSA-163200	7.91201131559e-21	0.8	MT-CO3 NDUFAF7 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
GO:0070069	2.4476478307e-20	0.666666666667	MT-CO3 MT-CO2 UQCRC1 COX6C UQCRQ UQCR10 UQCRFS1 MT-CO1 UQCRH MT-CYB	cytochrome complex
WP:WP111	1.02511584904e-19	0.733333333333	MT-CO3 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	Electron transport chain OXPHOS system in mitochondria
REAC:R-HSA-1428517	5.08975826399e-19	0.8	MT-CO3 NDUFAF7 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	The citric acid (TCA) cycle and respiratory electron transport
KEGG:00190	6.54791780711e-19	0.733333333333	MT-CO3 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	Oxidative phosphorylation
KEGG:04714	1.04929979982e-18	0.8	MT-CO3 NDUFAF7 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	Thermogenesis
KEGG:04932	2.90241221859e-18	0.733333333333	MT-CO3 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	Non-alcoholic fatty liver disease
WP:WP4396	4.79607308226e-18	0.733333333333	MT-CO3 MT-CO2 UQCRC1 UQCRH UQCRQ COX7A2L UQCR10 UQCRFS1 MT-CO1 COX6C MT-CYB	Nonalcoholic fatty liver disease

Showing 1 to 10 of 207 entries

Edges

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
COX5A	COX4I1	0.999	0.984	structurally_consistent (dimer)
MT-CO2	COX4I1	0.999	0.89	structurally_consistent (dimer)
UQCRB	UQCRC1	0.999	0.986
UQCRC2	UQCRC1	0.999	0.958	structurally_consistent (dimer)
UQCRC2	UQCRQ	0.999	0.96	structurally_consistent (P47985) structurally_consistent (dimer)
UQCRC2	UQCRFS1	0.999	0.966	structurally_consistent (dimer)
LYRM7	UQCRFS1	0.998	0.07
UQCRC2	MT-CO2	0.998	0.83	structurally_consistent (P13073)
UQCRQ	PTGES2	0.998	0.11
UQCRQ	UQCRC1	0.998	0.962

Showing 1 to 10 of 248 entries

Related Complexes

Genename	Complexes
MT-CYB	huMAP3_02983.1 huMAP3_06133.1 huMAP3_08223.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
COX7A2L	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
COX6C	huMAP3_04820.1 huMAP3_07696.1 huMAP3_10623.1 huMAP3_10718.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
UQCRFS1	huMAP3_01826.1 huMAP3_04728.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_09982.1 huMAP3_10294.1 huMAP3_10458.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14018.1 huMAP3_14580.1
MT-CO3	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07840.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1
COX7A2	huMAP3_01629.1 huMAP3_03863.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_10024.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
UQCRH	huMAP3_00773.1 huMAP3_07497.1 huMAP3_08223.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_14574.1
UQCR10	huMAP3_02983.1 huMAP3_07497.1 huMAP3_08223.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12457.1
UQCRQ	huMAP3_02983.1 huMAP3_05463.1 huMAP3_06133.1 huMAP3_07069.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
COX6A1	huMAP3_07005.1 huMAP3_08546.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
MT-CO2	huMAP3_00773.1 huMAP3_05665.1 huMAP3_07005.1 huMAP3_08024.1 huMAP3_08311.1 huMAP3_08386.1 huMAP3_09906.1 huMAP3_10623.1
PTGES2	huMAP3_05353.1 huMAP3_08546.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_12970.1 huMAP3_14560.1 huMAP3_14580.1
UQCRC1	huMAP3_06133.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_09982.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14018.1 huMAP3_14560.1 huMAP3_14580.1
COX5A	huMAP3_01464.1 huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
NDUFAF7	huMAP3_01629.1 huMAP3_01826.1 huMAP3_07021.1 huMAP3_07227.1 huMAP3_07890.1 huMAP3_10024.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_13468.1 huMAP3_14910.1
UQCRC2	huMAP3_00773.1 huMAP3_06247.1 huMAP3_07245.1 huMAP3_07497.1 huMAP3_08223.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12457.1 huMAP3_12621.1
LYRM7	huMAP3_00475.1 huMAP3_01826.1 huMAP3_04728.1 huMAP3_06034.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_07890.1 huMAP3_09941.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14580.1
UNG	huMAP3_01826.1 huMAP3_03561.1 huMAP3_04728.1 huMAP3_05671.1 huMAP3_07021.1 huMAP3_07870.1 huMAP3_08389.1 huMAP3_09058.1 huMAP3_10294.1 huMAP3_10341.1 huMAP3_10623.1 huMAP3_10642.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12510.1 huMAP3_14580.1
COX7C	huMAP3_04820.1 huMAP3_07696.1 huMAP3_10623.1 huMAP3_10718.1 huMAP3_11232.1 huMAP3_12457.1
UQCRB	huMAP3_02983.1 huMAP3_06133.1 huMAP3_07840.1 huMAP3_08546.1 huMAP3_09600.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14560.1 huMAP3_14580.1
SHISA2	huMAP3_03681.1 huMAP3_05353.1 huMAP3_10623.1
MT-CO1	huMAP3_01464.1 huMAP3_06639.1 huMAP3_07696.1 huMAP3_07840.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1
COX4I1	huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10623.1 huMAP3_10725.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_14580.1
COX6B1	huMAP3_03863.1 huMAP3_07005.1 huMAP3_08024.1 huMAP3_08055.1 huMAP3_09906.1 huMAP3_10024.1 huMAP3_10294.1 huMAP3_10623.1 huMAP3_12170.1 huMAP3_12457.1 huMAP3_12621.1 huMAP3_13252.1 huMAP3_14580.1 huMAP3_14899.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10623.1

Complex Portal: CPX-24633